Impact of Opportunistic Infections on the Quality of Life and Treatment Outcomes in HIV Patients of Tiruchendur Taluk, Tamil Nadu, India

Abstract

Opportunistic infections (OIs) are a significant contributor to the morbidity and mortality of HIV
patients, severely impacting their quality of life (QoL) and treatment outcomes. This review
explores the effect of OIs on the physical, psychological, and socio-economic well-being of HIV
patients in Tiruchendur Taluk, Tamil Nadu. Tuberculosis (TB), candidiasis, cryptococcosis,
Pneumocystis jirovecii pneumonia (PJP), and cytomegalovirus (CMV) infections remain prevalent
and have been associated with increased hospitalization rates, ART failure, and decreased patient
survival. The review highlights the need for early detection, adherence to ART, and comprehensive
healthcare interventions to improve the QoL of HIV patients and enhance treatment success.