Higher education's learning process uses the Collaborative Project-Based Learning (CPBL) Model, which is implemented into the Modular Object Oriented Dynamic Learning Environment (MOODLE). This application program can change learning media web-based. The CPBL model is learning that uses problems with projects that can be identified in scenarios to increase knowledge and understanding of the learning process. The CPBL Learning Model using Moodle has excellent potential in higher education because it provides knowledge construction and skills development related to interactions that result in a more essential learning process built to overcome problems in the teaching and learning process educators. This study aims to implement e-learning with the moodle-based CPBL model and Virtual Remote Labs (VRLs). Based on a conceptual review of the CPBL type of learning model, this paper explores Virtual Remote Labs (VRLs) using Moodle for concrete experiences in higher education. In the Moodle application, there are several learning activities to form groups using the CPBL model syntax. The Moodle application plugin is designed to upload and deliver learning materials, face-to-face, and practical work with VRLs using the CPBL model syntax in universities. This study requires careful planning, dynamics, sufficient to form collaborative groups and the relevance of student practice related to the use of VRLs technology with Moodle for changing teaching roles and autonomy in the management of learning in universities.